意大利那不勒斯費(fèi)德里科二世大學(xué)2023年招聘博士后職位（力學(xué)生物學(xué)）
那不勒斯費(fèi)德里科二世大學(xué)， 即Università degli studi di Napoli Federico II 是那不勒斯市主要，是古老的大學(xué)學(xué)府。該大學(xué)于1224年由神圣羅馬帝國皇帝和那不勒斯西西里國王腓特烈二世創(chuàng)建。最初是專門為了培養(yǎng)政府人員而建設(shè)的，其政治及司法學(xué)術(shù)傳統(tǒng)較為突出。1978年9月7日大學(xué)正式以創(chuàng)始人的名字命名。學(xué)校是意大利第一所國屬大學(xué)，這點(diǎn)就足夠使他成為歐洲最古老的一所大學(xué)。該大學(xué)法學(xué)系和文學(xué)系德高望重，具有權(quán)威性，著名的希臘語言文化學(xué)者M(jìn)ARCELLO GIGANTE就在這里任教。該校已在90年代， 在意大利大學(xué)排名第二位，僅次于羅馬大學(xué)。
那不勒斯費(fèi)德里科二世大學(xué)獲得中國教育部認(rèn)證。它是歐洲第一所專門用來培養(yǎng)管理人員的學(xué)校，也是世界上最古老的大學(xué)之一。著名哲學(xué)家托馬斯·阿奎納就畢業(yè)于該校。
Postdoc In Mechanobiology
Universities and Institutes of Italy
Italy
January 01, 2024
Contact:N/A
Offerd Salary:Negotiation
Location:N/A
Working address:N/A
Contract Type:Other
Working Time:Full time
Working type:N/A
Ref info:N/A
29 Oct 2023
Job Information
Organisation/Company
Department of Molecular Medicine and Medical Biotechnology, Federico II University of Naples, Italy
Research Field
Engineering
Researcher Profile
Recognised Researcher (R2)
Country
Italy
Application Deadline
1 Jan 2024 - 23:00 (UTC)
Type of Contract
To be defined
Job Status
Full-time
Hours Per Week
To be defined
Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
ABOUT THE POSITION We are looking for a postdoctoral researcher to join the Maiuri team at the Department of Molecular Medicine and Medical Biotechnology, Federico II University of Naples, Italy. Our group studies how cells sense and react to mechano-chemical stimuli coming from the surrounding micro-environment. Particularly, we are interested to investigate how those stimuli impact on the cell nucleus.
ONGOING RESEARCH PROJECTS
Nuclear Volume Cell and nuclear volumes are related and they constantly grow during the cell cycle. Since alterations of nuclear shape and size are well recognized hallmarks of cancer, we are interested in develop a method to measure the nuclear volume. Such method would allow us to study the nucleus-to-cell volume ratio in homeostasis, investigating not only its variation during the cell cycle but also how it is perturbed upon tumor transformation. Different techniques have been proposed to quantify the cell volume, with a variety of accuracy and sensitivity. However, none of them is able to measure simultaneously cell and nuclear volumes of individual cells in real-time https: // www. biorxiv.org/content/10.1101/2022.06.07.494975v1.
The intrinsic shape of the nucleus While the nuclei of most cells tend to be either round or oval, various diseases are associated with alterations in the shape of the cell nucleus. An abnormal nuclear shape and size is associated with cancer, in fact, it is one of the key diagnostic tools used in identifying malignant cells. Moreover, mutations in genes encoding lamins, one of the major structural components of the nucleoskeleton, are leading to a variety of disorders, including muscular dystrophy, dilated cardiomyopathy and progeria, and show cells with characteristic perturbation of the nuclear shape. Yet, the basic mechanisms linking cell and nuclear shape, and which is the intrinsic shape of the nucleus, are still unclear. https: // www. nature.com/articles/s41467-023-37064-0; https: // www. nature.com/articles/s41467-020-15910-9
TYPE OF CONTRACT Two years postdoctoral research fellowship (~30000歐元/y).
REQUIRED SKILLS PhD or equivalent degree in either Biotechnology, Bioengineering or other related fields. Proficiency in basic cell biology and imaging. Experience in molecular biology and/or in microfabrication, would be considered a plus.
RequirementsAdditional InformationWork Location(s)
Number of offers available
1
Company/Institute
Department of Molecular Medicine and Medical Biotechnology, Federico II University of Naples, Italy
Country
Italy
Where to apply
Website
https: // jobrxiv.org/job/department-of-molecular-medicine-and-medical- biotechnol…
Contact
Website
https:// www. unina.it/home
STATUS: EXPIRED
