一、中心簡介
首都醫(yī)學(xué)科學(xué)創(chuàng)新中心（簡稱創(chuàng)新中心）是北京市新成立的具有獨立法人資格的新型研發(fā)機構(gòu)。創(chuàng)新中心以推動醫(yī)學(xué)科學(xué)發(fā)展、改善人類健康為目標(biāo)，開展生物醫(yī)學(xué)研究，致力于提升醫(yī)學(xué)科學(xué)創(chuàng)新與成果轉(zhuǎn)化能力，提高疾病診斷和治療水平。我們將匯聚世界高水平科學(xué)家及其科研團隊，與首都醫(yī)學(xué)教育和科學(xué)研究優(yōu)質(zhì)資源緊密合作，打造多學(xué)科交叉融合的科研平臺，綜合自由探索、醫(yī)學(xué)目標(biāo)導(dǎo)向、有組織科研等途徑，實踐新型科研模式和體制機制，逐步推進醫(yī)教研產(chǎn)的深度融合，培養(yǎng)適應(yīng)醫(yī)學(xué)科學(xué)創(chuàng)新發(fā)展的優(yōu)秀人才。
二、實驗室介紹
黃亞平博士于2013年和2018年分別在武漢大學(xué)和清華大學(xué)獲得學(xué)士和博士學(xué)位，之后在美國德克薩斯大學(xué)西南醫(yī)學(xué)中心（UT Southwestern Medical Center）從事博士后研究，并于近日加入首都醫(yī)學(xué)科學(xué)創(chuàng)新中心（CIMR）創(chuàng)建獨立實驗室。實驗室將主要研究一類熱休克蛋白（也叫分子伴侶）HSP40家族的重要生理學(xué)功能，尤其在維持基因組穩(wěn)定性、天然免疫和糖代謝等途徑中的功能和作用機制，及其在腫瘤、自體免疫疾病和代謝疾病中的作用。
三、實驗室研究方向
本實驗室將綜合利用傳統(tǒng)生物化學(xué)和細(xì)胞生物學(xué)、蛋白質(zhì)組學(xué)、結(jié)構(gòu)生物學(xué)、代謝組學(xué)、高通量篩選以及小鼠模型等手段，開展以下研究：
解析HSP40家族在DNA損傷修復(fù)、天然免疫及糖代謝等重要生理學(xué)過程中的作用和機制；
探究HSP40在腫瘤、自體免疫疾病和代謝疾病等人類復(fù)雜疾病發(fā)生發(fā)展和治療中的作用；
開發(fā)基于HSP40的抗腫瘤、抗感染藥物和方法。
代表性一作文章
Nature Communications, 2023, 14: 5246.
Cell Discovery, 2023, 9: 107.
Cell Discovery, 2019, 5: 57.
PNAS, 2018, 115: 9598-9603
(Another story about DNAJA2 regulating insulin signaling and glucose metabolism, coming soon)
四、招聘崗位
01【助理研究員】
1）主要職責(zé)
1. 在課題組長指導(dǎo)下獨立開展研究工作；
2. 協(xié)助指導(dǎo)研究生工作以及撰寫論文或基金申請。
2）任職要求
1. 具有腫瘤生物學(xué)、生物化學(xué)（尤其蛋白質(zhì)結(jié)構(gòu)生物化學(xué)）、細(xì)胞生物學(xué)、分子生物學(xué)、免疫學(xué)或其他相關(guān)生物醫(yī)學(xué)領(lǐng)域的研究背景，已獲得博士學(xué)位且至少有兩年博士后研究經(jīng)歷；
2. 以第一作者身份在領(lǐng)域內(nèi)主流期刊上發(fā)表過研究論文，能夠獨立開展研究工作；
3. 熟練掌握生物化學(xué)、細(xì)胞生物學(xué)、分子生物學(xué)、動物實驗等基本實驗操作；
4. 具備獨立開展科研工作、指導(dǎo)研究生的能力，科學(xué)態(tài)度嚴(yán)謹(jǐn)；
5. 具備流利的英語讀寫和日常交流能力，能夠使用英文撰寫論文。
02【博士后】
1）主要職責(zé)
1. 在課題組長指導(dǎo)下獨立開展研究工作；
2. 協(xié)助指導(dǎo)研究生工作以及撰寫論文或基金申請。
2）任職要求
1. 具有腫瘤生物學(xué)、生物化學(xué)（尤其蛋白質(zhì)結(jié)構(gòu)生物化學(xué)）、細(xì)胞生物學(xué)、分子生物學(xué)、免疫學(xué)或其他相關(guān)生物醫(yī)學(xué)領(lǐng)域的研究背景，即將獲得博士學(xué)位或已獲得博士學(xué)位（原則上不超過2年）；
2. 以第一作者身份在領(lǐng)域內(nèi)主流期刊上發(fā)表過或即將發(fā)表研究論文，能夠獨立開展研究工作；
3. 熟練掌握生物化學(xué)、細(xì)胞生物學(xué)、分子生物學(xué)、動物實驗等基本實驗操作；
4. 具備獨立開展科研工作、指導(dǎo)研究生的能力，科學(xué)態(tài)度嚴(yán)謹(jǐn)；
5. 具備流利的英語讀寫和日常交流能力，能夠使用英文撰寫論文。
五、福利待遇
1. 根據(jù)應(yīng)聘者的工作經(jīng)驗和能力，提供具有市場競爭力的薪酬（詳情面談）；
2.享受五險一金、帶薪年假、體檢和補充醫(yī)療保險等；
3.支持個人職業(yè)發(fā)展，提供必要的工作相關(guān)專業(yè)培訓(xùn)。
六、申請方法
應(yīng)聘者請將個人簡歷、研究興趣或計劃，以及2-3名推薦人的姓名及聯(lián)系方式，以及其他能證明科研能力的相關(guān)電子文件發(fā)送到郵箱huangyp@cimrbj.ac.cn，郵件主題請注明“應(yīng)聘者名字+具體應(yīng)聘職位”。
聯(lián)系人：黃老師
聯(lián)系地址：北京市豐臺區(qū)右安門外西頭條10號-首都醫(yī)學(xué)科學(xué)創(chuàng)新中心
本招聘長期有效，至招聘到合適人選為止。
ABOUT CIMR
The Chinese Institutes for Medical Research (CIMR) is a newly founded institution dedicated to fundamental and translational medical research. The CIMR is located at the main campus of the Capital Medical University, Beijing, China and committed to building a scientist-centered governance framework and fostering a diverse and inclusive work environment.For more information, please visit our website: www.cimrbj.ac.cn
Laboratory Introduction
The Huang laboratory at CIMR is interested in identifying the fundamental physiological functions of heat shock protein 40s (HSP40s) in critical biological pathways including genome maintenance, innate immunity and glucose metabolism, and their implications in pathogenesis of human diseases, such as cancer, autoimmune disease and metabolic disorder.
A.Major Research Projects
a. Decoding the functions and functional mechanisms of HSP40 in critical biological pathways including genome maintenance, innate immunity and glucose metabolism.
b. Exploring the functions of HSP40 in the pathology and treatment of human disease, such as cancer, autoimmune disease and metabolic disorder.
c. Developing HSP40-based therapeutics for human diseases.
B.Representative Publications
Nature Communications, 2023, 14: 5246.
Cell Discovery, 2023, 9: 107.
Cell Discovery, 2019, 5: 57.
PNAS, 2018, 115: 9598-9603
(Another story about DNAJA2 regulating insulin signaling and glucose metabolism, coming soon)
Open Positions
Research assistant investigator
Main Responsibilities
a. Conducting research projects independently.
b. Assisting PI to mentor graduate students, write grant proposals and manuscripts.
Qualifications
a. Backgrounds in cancer biology, biochemistry (biochemistry and structural biology of proteins preferred), cell biology, molecular biology, immunology, or other related biomedical fields. A Ph.D degree and at least two years of postdoc experience is required.
b. Published research papers as the first author in reputable journals in the field.
c. Strong research experience in molecular biology, biochemistry, cell biology and/or mouse studies.
d. Self-motivated and independent researcher capable of independently conducting scientific research and assisting to supervise graduate students.
e. Proficient in English reading, writing, and daily communication. Capable of writing papers in English.
Postdoctoral Researcher
Main Responsibilities
a. Conducting research projects independently.
b. Assisting PI to mentor graduate students, write grant proposals and manuscripts.
Qualifications
a. Backgrounds in cancer biology, biochemistry (biochemistry and structural biology of proteins preferred), cell biology, molecular biology, immunology, or other related biomedical fields. Either about to obtain a Ph.D or recently obtained a Ph.D degree (ideally within the last 2 years).
b. Published or about to publish research papers as the first author in reputable journals in the field.
c. Strong research experience in molecular biology, biochemistry, cell biology and/or mouse studies.
d. Self-motivated and independent researcher capable of independently conducting scientific research and assisting to supervise graduate students.
e. Proficient in English reading, writing, and daily communication. Capable of writing papers in English.
Welfare Treatment
a.Competitive salary based on the job applicant's work experience and abilities (salary negotiable).
b. Social insurance, paid annual leave, physical examination and supplementary medical insurance, etc.
c.Supporting personal career development and providing necessary job related professional training.
How to apply
To apply, please send personal resume, research interest or plan, the names and contacts of 2-3 referees and other materials demonstrating research capabilities to huangyp@cimrbj.ac.cn, and indicate the applicant's name and specific job position in the email subject.
Contact person: Yaping Huang
This recruitment is valid for the long term until a suitable candidate is recruited.
信息來源于網(wǎng)絡(luò)，如有變更請以原發(fā)布者為準(zhǔn)。
來源鏈接：
https://mp.weixin.qq.com/s/rEd19xgVklTjSHIg8errOA
